The Board of Directors of Chordate Medical Holding AB (publ) proposes a rights issue of approximately 51,3 MSEK

NOT FOR RELEASE, DISTRIBUTION OR PUBLICATION, IN WHOLE OR IN PART, EITHER DIRECTLY OR INDIRECTLY, WITHIN OR INTO THE UNITED STATES, AUSTRALIA, BELARUS, HONG KONG, JAPAN, CANADA, NEW ZEALAND, RUSSIA, SWITZERLAND, SINGAPORE, SOUTH AFRICA, SOUTH KOREA OR IN ANY OTHER JURISDICTION WHERE THE RELEASE, DISTRIBUTION OR PUBLICATION OF THIS PRESS RELEASE WOULD BE UNLAWFUL OR WOULD REQUIRE ADDITIONAL REGISTRATIONS OR OTHER MEASURES.

The Board of Directors of Chordate Medical Holding AB (publ) (”Chordate Medical” or the ”Company”), which is listed on Nasdaq First North Growth Market (”Nasdaq First North”), has today, November 17, 2022, proposed that an extraordinary general meeting on December 5, 2022, resolve to carry out an issue of shares with preferential rights for the Company's shareholders amounting to approximately 51,3 MSEK (the “Rights Issue”).The Company has received subscription undertakings from main shareholders and members of the Board of Directors and management corresponding to approximately 33 percent of the Rights Issue. Notice to the extraordinary general meeting will be published through a separate press release. The Rights Issue enables Chordate Medical to penetrate selected markets in order to achieve strategic – and potentially value-creating – targets.

Background and reasons for the Rights Issue

Chordate Medical is a Swedish company that, through its wholly-owned subsidiary Chordate Medical AB, develops, sells and markets K.O.S (Kinetic Oscillation Stimulation), a patented and CE-marked nerve stimulation technology for the treatment of chronic migraine and chronic rhinitis.

K.O.S is a simple and cost-effective treatment without drugs that has demonstrated, in several clinical studies, to be free of unexpected side effects. In a first subgroup analysis, consisting of 92 German patients from the Company's patient study on K.O.S against chronic migraine that ended in August 2022, a statistically significant reduction in the number of headache days could be reported. The subgroup results provide support for market activities within the migraine market and the ongoing work with the Company's FDA application. The market for treatments against migraine is larger than the market for treatments for rhinitis, so success in the migraine area is a significant step in Chordate Medical's exit strategy, which consists of three parts:

• Broad patent portfolio – Chordate Medical has 71 granted patents grouped into 9 patent families in 26 markets and 3 more patent applications are pending.

• Scientific evidence – The second part of the strategy is to produce scientifically based evidence for treatment’s clinical effect on the two indications.

• Proof of concept – The third part is to show early market penetration in selected markets in order to demonstrate the value of the technology.

The Board of Directors assesses that existing working capital is not sufficient to conduct business for the next twelve-month period. In order to accelerate the work towards an exit, primarily through continued investments in the migraine market with the support of the latest study results, the Board of Directors has resolved to propose the Rights Issue. If fully subscribed, the Rights Issue is estimated to raise approximately 51.3 MSEK to Chordate Medical before costs related to the issue. The proceeds from the issuance is intended to be distributed in accordance with the percentages set out below and, in the event that not all measures can be implemented, according to the following priority:

• 20% is allocated to market registration and product releases.

• 25% is allocated to supporting clinical studies.

• 55% is allocated to market strategic activities and other working capital.

Terms and conditions of the Rights Issue

The Board of Directors’ proposal to the extraordinary general meeting includes that the Rights Issue be carried out in accordance with the main conditions set out below.

  • The right to subscribe for shares with preferential rights shall vest in those who are registered as shareholders in the Company on the record date, 12th December 2022 pro rata to their shareholdings in the Company. One (1) existing share entitles to one (1) subscription right.
  • Twenty (20) subscription rights entitles to subscription of thirteen (13) shares in the Company.  
  • The Rights Issue will increase the number of shares by maximum 102 513 047.
  • The subscription price is 0,50 SEK per share. No commission is charged.
  • The subscription period runs from December 14, 2022, up to and including December 29, 2022.
  • If not all of the shares are subscribed for through the exercise of subscription rights, the Board of Directors shall, within the scope of the maximum amount of the Rights Issue, resolve on allotment of shares subscribed for without the exercise of subscription rights, whereby allotment (i) firstly, shall be made to those who have also subscribed for shares through the exercise of subscription rights, regardless of whether the subscriber was a shareholder on the record date or not, and, in the event allotment to these cannot be made in full, allotment shall be made pro rata in relation to their subscription through their subscription rights and, where this is not possible, through a drawing of lots; and (ii) secondly, shall be made to others who have subscribed for shares in the Rights Issue without exercise of subscription rights and, in the event allotment to these cannot be made in full, allotment shall be made pro rata in relation to the number of shares each subscribed for and, where this is not possible, through a drawing of lots.
  • If the Rights Issue is fully subscribed, the Company will receive approximately 51,3 MSEK before issue costs.
  • Trading in paid subscription shares (Sw.BTA”) is expected to start at Nasdaq First North from 14 December 2022 until the Rights Issue is registered by the Swedish Companies Registration Office (Sw.Bolagsverket”). The Rights Issue is expected to be registered around mid January 2023.

Change of share capital and number of shares and dilution

Through the Rights Issue, the number of shares in Chordate Medical will increase by a maximum of 102 513 047 shares, from 157 712 380 shares to 260 225 427 shares, and the share capital will increase by maximum 25 628 261,75 SEK, from 39 428 095 SEK to 65 056 356,75 SEK. This means that existing shareholders who choose not to participate in the Rights Issue will, if fully subscribed, experience a dilution of approximately 39.4 per cent of their votes and capital in the Company.

Subscription undertakings

In connection with the Rights Issue, the Company has received subscription undertakings from the Company’s existing shareholders and members of the Board of Directors and management amounting to a total of approximately 16,7 MSEK. Those who have entered into subscription undertakings are HAWOC Investment AB, Sifonen AB, Tommy Hedberg, Magnus Brandberg, Bevaclean AB and Anders Weilandt. The subscription undertakings correspond to approximately 33 percent of the Rights Issue. No renumeration is paid for the subscription undertakings submitted.

Preliminary timetable for the Rights Issue  

5 December 2022 Extraordinary general meeting

8 December 2022 Last day of trading including the right to receive subscription rights

9 December 2022 First day of trading excluding the right to receive subscription rights

12 December 2022 Record date for participation in the Rights Issue

13 December 2022 Estimated date for publication of Prospectus

14-29 December 2022 Subscription period.

14-23 December 2022 Trading in subscription rights.

14 December 2022 Trading in paid subscription shares (Sw.BTA”) until the Rights Issue is registered by the Swedish Companies Registration Office (Sw.Bolagsverket”).

2 January 2023 Expected publication of subscription result in the Rights Issue.

Prospectus

Full terms and conditions and instructions for the Rights Issue, as well as other information about the Company will be presented in the prospectus that the Company is expected to publish around December 13, 2022 (the "Prospectus").

Advisers

Västra Hamnen Corporate Finance AB acts as financial adviser and Wistrand Advokatbyrå acts as legal adviser to Chordate Medical in connection with the Rights Issue.

Important information

The information in this press release neither contains nor constitutes an offer to acquire, subscribe or otherwise trade with shares, warrants or other securities in Chordate Medical. No measure has been taken and no measure will be taken to permit an offer to the public in any other jurisdiction other than Sweden. Any invitation to the persons concerned to subscribe for shares in Chordate Medical will only be made through the Prospectus which will be published by the Company around 13 December 2022 on Chordate Medical’s website, www.chordate.com. The Swedish Financial Supervisory Authority’s upcoming approval of the Prospectus shall not be understood as an approval of the Company’s shares, warrants or other securities. This press release is not a prospectus within the meaning of the Prospectus Regulation (EU) 2017/1129 (the ”Prospectus Regulation”) and this press release neither identifies nor purports to identify risks (direct or indirect) that may be connected with an investment in shares, warrants or other securities in Chordate Medical. Any investment decision should, in order for an investor to fully understand the risks and benefits associated with the decision to participate in the rights issue, be made solely based on the information in the Prospectus. An investor is therefore advised to read the entire Prospectus.

The information in this press release is not for release, publication or distribution, in whole or in part, directly or indirectly, within or into the United States, Australia, Belarus, Hong Kong, Japan, Canada, New Zealand, Russia, Switzerland, Singapore, South Africa, South Korea or in any other jurisdiction where such actions would be unlawful, subject to legal restrictions or require other measures in addition to those required under Swedish law. Measures in violation of the restrictions may constitute a breach of relevant securities law.

No shares, warrants or other securities in Chordate Medical has been registered, and no shares, warrants or other securities will be registered under the United States Securities Act of 1933, as amended (the ”Securities Act”), or the securities laws of any state or other jurisdiction in the United States, and may not be offered, sold or otherwise transferred, directly or indirectly, in or into the United States, except pursuant to an applicable exemption from, or in a transaction not subject to, the registration requirements of the Securities Act and in compliance with the securities laws of the relevant state or other jurisdiction in the United States.

Within the European Economic Area (the ”EEA”), no offer of shares, warrants or other securities (the ”Securities”) is made to the public in any other country other than Sweden. In other Member States of the European Union (the ”EU”), such an offer of Securities can only be made in accordance with the exemptions in the Prospectus Regulation (EU) 2017/1129. In other countries in the EEA that have implemented the Prospectus Regulation in national legislation, such an offer of Securities can only be made in accordance with the exemptions in the Prospectus Regulation and in accordance with any relevant implementation measures. In other countries in the EEA that have not implemented the Prospectus Regulation in national legislation, such an offer of securities can only be made in accordance with the applicable exemptions in national legislation.

In the United Kingdom, this press release, and other material in relation to the securities referred to herein, is only distributed to and directed at, and an investment or investment activity attributable to this press release is only available to, and will only be able to be exercised by ”qualified investors” (within the meaning of the UK version of Regulation 2017/1129 which has been incorporated into UK law by the European Union (Withdrawal) Act 2018) who are (i) persons who have professional experience in investments and fall within the definition of ”investment professional” in article 19(5) of the UK Financial Services and Markets Act 2000 (Financial Promotion) Order 2005 (the ”Order”), or (ii) ”high net worth entities” etcetera who fall within article 49(2)(a)-(d) of the Order; or (iii) such other persons whom such investment or investment activity may lawfully be directed to according to the Order (all such persons are collectively referred to as ”relevant persons”). An investment or investment activity to which this press release relates is available in the UK only to relevant persons and will only be carried out with relevant persons. Persons who are not relevant persons should not take any action on the basis of this press release and should not act or rely on it.

This press release may contain certain forward-looking information that reflect the Company’s current view of future events as well as financial and operational development. Words such as ”intend”, ”assess”, ”expect”, ”may”, ”plan”, ”estimate” and other expressions involving indications or predictions regarding future development or trends, not based on historical facts, identify forward-looking statements. Forward-looking statements is inherently associated with both known and unknown risks and uncertainties as it is dependent on future events and circumstances. Forward-looking statements is not a guarantee of future performance or development, and the actual outcome may differ materially from what is stated in forward-looking statements.

Chordate Medical presents interim report for Q3 2022

Chordate Medical Holding AB (publ) ("Chordate") (Nasdaq First North Stockholm: CMH) will publish its interim report for Q3 2022 on Friday November 18, 2022, at 08:30 am.

A webcast teleconference with CEO Anders Weilandt will be broadcast live on Friday November 18 at 02:00 pm. The conference will be followed by a Q&A session. The presentation will be held in Swedish. It is possible to follow the conference via computer or mobile devices.

To register for the web conference, please follow this link:

https://attendee.gotowebinar.com/register/1081159006671885835

Places are limited so we recommend registering well in advance to secure a place.

A recording of the web conference will be available on the company's website www.chordate.com and on Västra Hamnen Corporate Finance YouTube channel after the conference has ended.

Statistical significance confirmed in final analysis of Chordate’s PM007 multicenter clinical study of the K.O.S technology for preventive treatment of chronic migraine

Chordate Medical Holding AB (publ) ("Chordate") (Nasdaq FirstNorth Stockholm: CMH), a specialty medtech company that focuses on developing neuromodulating systems for treating chronic migraine, today announces that final data analysis confirms the statistically significant results from the subgroup analysis presented as a poster early September at the Migraine Trust International Symposium 2022, London.

Primary Objective
The statistical analysis of the Full Analysis Set derived from a total of 140 randomized subjects, randomized to receive active K.O.S-treatment, or sham-treatment, reached the Primary Endpoint goal by demonstrating a significantly reduced number of monthly headache days (MHD) with moderate to severe intensity from baseline.

Secondary Objectives
Response Rate data defined as ≥30% reduction in MHD with moderate to severe intensity from baseline demonstrated significance. Other Secondary endpoints demonstrated significant or favorable results.
The study data contains no treatment related serious adverse events.
The final study data will be communicated by Chordate in detail once the first scientific article manuscript has been accepted for publication.
“The value for us as a company to have the final data confirming this level of success, and added to our strategic scientific evidence base, is simply immense. By this we can deliver in full on the hypothesis that K.O.S, a non-drug medical device solution for preventive treatment of chronic migraine, is a valid treatment option, that can change the lives of many patients to the better. As we are cautious about preserving the scientific news-value in the coming publication of one or more articles, we will have to await approval-for-publication before we communicate the results in detail”, says Anders Weilandt, CEO of Chordate.

About the PM007 trial
This randomized, sham-controlled, double-blind, multicenter study was conducted at five neurology clinics in Germany and four in Finland. The study randomized 140 subjects and was designed to evaluate the efficacy and safety of the K.O.S-treatment. Primary endpoint was to detect mean change from baseline (4-week screening period, 4-week follow-up period) in monthly headache days with moderate to severe intensity, following weekly treatments for six weeks. Fifty percent of the subjects received active K.O.S-treatment from the S211 investigative device, and fifty percent received a validated sham/placebo treatment from the same equipment.

The study enrolled subjects with diagnosed chronic migraine (≥15 days/month of headache, whereof >8 days with migraine) and saw the last subject leaving the study at the beginning of August 2022.

Chordate Medical launches market introduction of migraine treatment in Finland

Chordate Medical ("Chordate", "the company") has engaged a market expert in Finland to introduce the company's product K.O.S for preventive migraine treatment on the Finnish market. After the very positive subgroup results and the fact that Finnish clinics are part of the larger study that Chordate is conducting, the company believes that the potential for a good reception from the Finnish market is high.

Chordate has recently completed a clinical study of preventive treatment for chronic migraine, including 97 German patients, who were treated at 5 neurology clinics. According to a published sub-analysis of the German results, K.O.S is indicated to be an effective and safe alternative for the preventive treatment of chronic migraine. And because K.O.S is a non-pharmaceutical option, it would provide a valuable addition to current treatment interventions, without the significant risk of unwanted side effects commonly seen with other preventive treatment options.

The total patient study includes, in addition to Germany, also 40 patients at 4 clinics in Finland, data is still subject to analysis but will be published to the market as soon as possible.

In the work for market access with the migraine indication, Chordate has gradually switched to engaging market experts to build up networks of opinion-leading neurologists, management of reimbursement issues, and early market activities. At the same time, the collaboration with the former distributor for the Nordic region has ended.

“With the fantastic results from the German subgroup analysis, we have received scientific support to broaden the investment in chronic migraine. In Finland, we now use a hired expert in launch and market access for MedTech. Kaija Hämäläinen has extensive experience from the neurology market and a wide network of contacts. In the wake of the German partial analysis, we see a clear potential in Finland that we immediately want to exploit, in the same way that we have already started work on market introduction in Germany, the UK and Israel”, says Anders Weilandt, CEO of Chordate.

Chordate CEO Anders Weilandt explains study results at Aktiedagen on September 12th

On Monday, September 12th, 11:00, Chordate's CEO Anders Weilandt will participate on Aktiespararnas event Aktiedagen Stockholm. He will mainly talk about the subgroup result of the migraine study PM007 on the K.O.S treatment that was presented in London on September 8, and what it means for the company. The subgroup result shows a statistically significant reduction in the number of headache days.

“This event will be a good opportunity for me to explain the very positive result from the subgroup analysis, how it should be interpreted and what it means for the company going forward”, says Anders Weilandt, Chordate CEO.

Aktiedagen takes place at Hotel Birger Jarl in Stockholm. To attend on site, register here. The event is streamed live at www.aktiespararna.se/tv/live and on Aktiespararna’s Youtube channel. No registration is required to follow the event digitally.

After the presentation, Anders Weilandt will participate in a Q&A and questions can be asked by sending an SMS to +46 79-347 98 45 or an email to event@aktiespararna.se. Questions can be sent in now or during the presentation.

Statistically significant reduction in number of headache days shown in subgroup analysis of Chordate’s PM007 multicenter clinical study of K.O.S-stimulation for preventive treatment of chronic migraine

Chordate Medical Holding AB’s (publ) ("Chordate")(Nasdaq FirstNorth Stockholm: CMH), a specialty medtech company that focuses on developing neuromodulating systems for treating chronic migraine, today announces that an abstract entitled “Kinetic Oscillation Stimulation for the treatment of chronic migraine – a subgroup analysis of a randomised controlled clinical trial” by Hoffmann, J. et al, is presented as a poster at the Migraine Trust International Symposium 2022, London.

The poster reveals that the subgroup analysis of the 46 German subjects receiving active K.O.S-treatment demonstrated a significantly reduced number of monthly headache days (MHD) with moderate to severe intensity from baseline, when compared to the 46 subjects receiving the sham treatment. The difference shown by the least square means (LSQ) of the ANCOVA model between the 4-week baseline period and treatment weeks 3-6 was -2.52 MHD (CI95%=[-4.52; -0.52], p=0.0140 and by non-parametric, stratified van Elteren test p=0.0092). The 4-week follow-up period results – after ending six weeks of stimulation – showed a reduction in LSQ of -2.70 MHD (CI95%=[-4.73;-0.68], p=0.093; van Elteren test p=0.0151), demonstrating a sustained improvement during the observation period.

Response defined as ≥30% reduction in MHD with moderate to severe intensity from baseline was achieved in 41.4% of the subjects receiving active K.O.S vs. 14.9% in the group receiving sham treatment. The treatment was also reported as well-tolerated without severe adverse events.

The authors concludes that this trial thus far indicates that K.O.S is an effective and safe option for the preventive treatment of chronic migraine. And further that as the K.O.S is a non-pharma alternative it would constitute a valuable expansion of the current therapeutic arsenal, without the significant risk of unwanted side effects commonly seen with other preventive treatment alternatives.

“It is remarkable to learn about such stunning effect from the German part of the PM007 study. The demonstrated level of response with K.O.S is also remarkable. This will indeed be a great support for our marketing and sales ambitions. The opportunity to make this subgroup analysis presented itself as the German clinics completed their work early. Our near-term task is now to compile the data from the completed study, and to get it published in its entirety”, says Anders Weilandt, CEO of Chordate.

About the PM007 trial

This randomized, sham-controlled, double-blind, multicenter study was conducted at five neurology clinics in Germany and four in Finland. The study enrolled 132 subjects and was designed to evaluate the efficacy and safety of the K.O.S-treatment. Primary endpoint was to detect mean change from baseline (4-week screening period, 4-week follow-up period) in monthly headache days with moderate to severe intensity, following weekly treatments for six weeks. Fifty percent of the subjects received active K.O.S-treatment from the S211 investigative device, and fifty percent received a validated sham/placebo treatment from the same equipment. The study enrolled subjects with diagnosed chronic migraine (≥15 days/month of headache, whereof >8 days with migraine) and saw the last subject leaving the study at the beginning of August 2022.

Chordate Medical Holding (publ) Interim Report April-June 2022

Summary of the period April–June 2022

  • Net turnover was SEK 19,538 (165,699)
  • Cash flow from operating activities amounted to SEK -5,812,210 (-5,183,818)
  • Profit/loss after financial items was SEK -5,962,508 (-5,056,471)
  • Profit/loss after tax was SEK -5,962,508 (-5,056,471)
  • Earnings per share were SEK -0.04 (-0.05)

Summary of the period January–June 2022

  • Net turnover was SEK 88,170 (267,328)
  • Cash flow from operating activities was SEK -13,228,791 (-10,695,986)
  • Profit/loss after financial items was SEK -13,341,661 (-10,855,568)
  • Profit/loss after tax was SEK -13,341,661 (-10,855,568)
  • Earnings per share were SEK -0.08 (-0.10)

COMMENTS FROM CEO ANDERS WEILANDT

RESULTS FROM THE MIGRAINE STUDY ARE COMING

The migraine study is finally finished after all of the coronavirus-related delays. Subgroup results from the German patient group will be made public on September 8 in London. Very exciting times. We are continuing to deepen our work with the market through directly engaged experts and are moving away from the distributor model.

  • The migraine study is presenting subgroup results in September and has been closed at the clinic
  • Market access agreement for Germany and Israel
  • Second phase in the FDA project continues
  • Study plan for support studies presented

Clinical study on migraines is complete

We have all waited a long time, but the study is now completed. The final Finnish patient went through their final follow-up at the beginning of August. All of the study data is now undergoing a rigorous control process and statistical analysis in order to serve as a basis for the final report and scientific articles for publication.

Since the same process has already been applied to the study data from the German patient group in the spring, the study organization was able to perform a so-called subgroup analysis. The 97 German patients left the study, and the five study clinics were formally closed at the end of 2021. Now that the Finnish study patients are done, the study is complete, with a total of 132 patients.

A subgroup analysis shows the results from a sample of the study data, for example gender, age span, other illnesses or, like in this case, geography. A subgroup result should be viewed as independent from the final study results but is often viewed as in-depth and interesting.

The subgroup results will be presented as a poster at the scientific symposium Migraine Trust International Symposium 2022, September 8–11 in London.

There are not really any words to describe how exciting this is. A large percentage of the study sample is represented, 97 out of 132, and it is clear that the expectations are high. The interim analysis from May 2019 was clearly very strong, so it is logical to hope for an even better result now. As always, though, science is always science, and a lot can happen in a study — which is what makes it so unbelievably exciting.

Model with market consultants underway in Germany and Israel

We are adding Germany as a focus market for the introduction of migraine treatment. Preparations have been ongoing for some time, and starting with the subgroup results from the migraine study that will be presented soon, we will be moving into high gear. For this, we signed a consulting services agreement with MTIGER GmbH in Munich. MTIGER’s consultants are highly competent and very experienced in the area of migraines. We are applying the concept of market access consults to Israel as well and are progressing with a consulting assignment for market access with one of the owners of our former Israeli distributor. Pharmore PSR Ltd has more than 30 years’ experience and a valuable contact network from the Israeli neurology market.

FDA project continues

We continue to work with the second phase of the project to register the migraine treatment after a first round with the US authority. We need to adapt a number of technical matters since the requirements on tests and verifications are different from those in the EU. The study results that will be presented shortly are also crucial for the continued steps that may need to be taken in the project.

Two new studies

To support our marketing and sales work, we are starting a follow-up study of 200 patients in several countries and a smaller pilot study that will target the patients who did not obtain results from treatment with CGRP inhibitors.

In the cards for 2022

Everything is progressing according to plan so far. We continue to follow the marketing plan for 2022. This applies naturally to both the migraine and the rhinitis indications, but we will have a stronger focus on migraine.

Kista, August 2022 Anders Weilandt, CEO

Chordate Medical presents interim report for Q2 2022

Chordate Medical Holding (publ) publishes its interim report for Q2 2022 on Tuesday, August 30, 2022, 08:30. On Wednesday, August 31 at 11:00 am, the company invites you to a teleconference with CEO Anders Weilandt.

After the conference, there will be a question-and-answer session. The presentation is held in English. It is possible to follow the conference via computer or mobile devices.

To register for the web conference, register via the following link:

https://attendee.gotowebinar.com/register/3519820819663201294

The number of places is limited, so we recommend registering well in advance to secure a place.

A recording of the web conference will be available after the conference on the company's website www.chordate.com and on the Västra Hamnen Corporate Finance YouTube channel.

Chordate Medical launches market introduction of migraine treatment in Germany

Chordate Medical ("Chordate", the "Company") has entered into an agreement with MTIGER GmbH, Germany, to introduce the company's product for preventive migraine treatment, K.O.S, on the German market. Following a detailed market analysis carried out by MTIGER, the agreement runs for an initial period of one year.

MTIGER will introduce the K.O.S treatment to leading neurologists in Germany on behalf of Chordate in both the private and public healthcare market. The ambition is also to resolve questions regarding reimbursement opportunities for the treatment. MTIGER will locally support the German part of the follow-up study PM010 in a small number of clinics.

According to a recently published analysis, the prevalence of migraine is 14.8 percent for women and 6 percent for men in the German population. According to the same analysis, 1.2 percent, approximately 1 million people, meet the criteria for the diagnosis of chronic migraine in Germany.

Chordate has recently completed a clinical study of preventive treatment for chronic migraine in which 97 German patients were included and treated at five neurology clinics. As previously communicated, a subgroup analysis of the German part of the study will be presented on September 8-11 at the neurology congress MTIS 2022 in London.

“During the analysis and stratification work of the German migraine market, we have for a long time gotten to know MTIGER's competence and network. The German healthcare market is extensive, but at the same time both complex and fragmented. Just like for the markets in the UK, Israel, and the gulf area, with this agreement we want to establish a collaboration with market experts who works focused and dedicated – under our management”, says Anders Weilandt, CEO of Chordate.

Chordate Medical begins market introduction of migraine treatment in Israel

Chordate Medical ("Chordate", the "Company") has entered into an agreement with the market relations company Pharmore PSR LTD, Israel, to introduce the companys product for preventive migraine treatment on the Israeli market.

The agreement details that Pharmore will present the K.O.S treatment to opinion leaders within the neurology/migraine field and then develop a broader market position. The agreement also includes that Pharmore will manage the implementation of the companys previously communicated clinical follow-up study PM010 at two Israeli clinics. The agreement with Chordates former distributor has been terminated.

"Because we assess the conditions for achieving results faster, we have now chosen to work with a focused market access project in Israel, the same way as in the UK. The key people with neurology market expertise at our former distributor have formed Pharmore and are a natural contracting party for the continued assignment. According to our assessment, Pharmore possesses the necessary competence in the specialist area of neurology, the structure of the healthcare market, reimbursement matters and marketing", says Anders Weilandt, CEO of Chordate.

For more information, please contact:
Anders Weilandt, CEO
anders.weilandt@chordate.com
Cell: +46 733-874277

The following documents can be retrieved from beQuoted
Chordate-Medical-begins-market-introduction-of-migraine-trea.pdf

About Chordate
Chordate Medical Holding AB (publ) is a medical technology company that for over ten years has developed, patented and CE-marked a new neuromodulation treatment technology for chronic nasal congestion (rhinitis) and chronic migraine. The company offers its product via distributors to clinics and hospitals in selected European markets, Israel, and Saudi Arabia. Chordate Medicals share is listed on Nasdaq First North Growth Market Stockholm (ticker: CMH). Read more at www.chordate.com

Chordate's Certified Adviser on Nasdaq First North Growth Market Stockholm is Västra Hamnen Corporate Finance AB, +46 40 200 250, ca@vhcorp.se.

N.B. The English text is an in-house translation of the original Swedish text. Should there be any disparities between the Swedish and the English text, the Swedish text shall prevail.